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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Ponatinib Influence on tumor growth Tumor size 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on tumor growth Tumor weight 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice p-STAT3 (Y705)
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice STAT3
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice